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Cheap flights from Mexico City to Panama City

One-way from $196, found by travellers in the last 7 days. The live price is checked when you book.

Departure
Return
Prices for nearby dates
Sat, Jan 2Any priceSun, Jan 3Any priceMon, Jan 4Any priceTue, Jan 5$196Wed, Jan 6Any priceThu, Jan 7Any priceFri, Jan 8Any priceSat, Jan 9Any price

Cheapest one-way tickets

Recent finds on different dates, for 1 adult. Booking opens on Aviasales, which shows baggage, fare rules and the live price.

Cheapest
$196
Aeromexico, flight AM 464Found 5 days ago, 1 adult
Check live price
8:45amMexico CityTue, Jan 5
Travel time 3h 48m, nonstopMEXPTY
1:33pmPanama CityTue, Jan 5
$230
Copa Airlines, flight CM 857Found 7 days ago, 1 adult
Check live price
2:00amMexico CityWed, Oct 28
Travel time 3h 41m, nonstopMEXPTY
6:41amPanama CityWed, Oct 28
$268
Aeromexico, flight AM 464Found 6 days ago, 1 adult
Check live price
8:50amMexico CityFri, Nov 27
Travel time 3h 56m, nonstopMEXPTY
1:46pmPanama CityFri, Nov 27
$270
Aeromexico, flight AM 464Found 3 days ago, 1 adult
Check live price
8:55amMexico CityMon, Feb 8
Travel time 3h 51m, nonstopMEXPTY
1:46pmPanama CityMon, Feb 8
$270
Aeromexico, flight AM 464Found yesterday, 1 adult
Check live price
8:40amMexico CitySat, Feb 20
Travel time 3h 51m, nonstopMEXPTY
1:31pmPanama CitySat, Feb 20

Round trips

The cheapest return tickets found recently, price for the whole trip.

Plan the rest of the trip

  • Mobile data in PanamaTravel eSIM from $7, installed before you fly.
    Compare plans
  • Getting from the airportTransfers and car hire in Panama City, booked ahead at a fixed price.
    See options
  • Things to do in Panama CityPopular tours from $30 per person.
    See ideas
  • Travel insuranceTravel insurance quotes for Panama from EKTA; check what each policy covers.
    Get a quote
  • Flight delayed?Delayed or cancelled? See which passenger rights cover this route.
    Check

Price calendar

The lowest one-way fare found for each day over the next 60 days. A dash means no recent fare; you can still pick that day.

October 2026

MoTuWeThFrSaSu12345678910111213141516171819202122232425$31726$35227–28$23029–30–31$306

November 2026

MoTuWeThFrSaSu1–2–3–4–5–6–7–8–9–10$28011–12–13–14–15–16–17–18–19–20–21–22–23–24–25–26–27$26828–29–30–

December 2026

MoTuWeThFrSaSu1–2–3–4–5–6–7–8–9–10–11–12–13–14–15–16–17–18–19–20–21–22–23–2425262728293031
$268 or lessGreen: the cheapest fifth of fares on this route. Lowest in these 60 days: Oct 28, $230.

Lowest fares by month

In the fares found this week, January 2027 has the lowest: from $196 one-way, against $270 in February 2027. Pick a month to see its cheapest date.

  1. Oct$230
  2. Nov$268
  3. Decno fares yet
  4. Jan$196
  5. Feb$270
  6. Marno fares yet
  7. Aprno fares yet
  8. Mayno fares yet
  9. Junno fares yet
  10. Julno fares yet
  11. Augno fares yet
  12. Sepno fares yet
$0$100$200$300OctNovDec$196JanFebMarAprMayJunJulAugSep
Show as a table
MonthCheapest one-wayDateStops
October$230Wed, Oct 28Nonstop
November$268Fri, Nov 27Nonstop
December—
January 2027$196Tue, Jan 5Nonstop
February 2027$270Sun, Feb 21Nonstop
March 2027—
April 2027—
May 2027—
June 2027—
July 2027—
August 2027—
September 2027—

Fares and weather by month

The lowest one-way fare found for each month, next to the weather in Panama City. Average daily high and low and monthly precipitation, 1991–2020 normals.

Oct2026NovDecJan2027FebMarAprMayJunJulAugSep
Lowest fare$230$268–$196$270–––––––
High °C31°31°32°32°33°33°33°32°32°32°32°31°
Low °C22°22°22°21°22°22°23°23°23°23°23°22°
Precipitation mm31125912524121471222242190221268

Source: Panama City on Wikipedia, CC BY-SA 4.0.

Questions travellers ask

What is the cheapest month to fly from Mexico City to Panama City?

In the fares found this week, January 2027 has the lowest: from $196 one-way, against $270 in February 2027.

What is the weather in Panama City in January 2027?

In January 2027, the cheapest month to fly, the average daily high in Panama City is 32 °C and the low 21 °C.

Are there direct flights from Mexico City to Panama City?

Yes. Recent fares include nonstop flights with Aeromexico and Copa Airlines.

How long is the flight from Mexico City to Panama City?

A nonstop flight takes about 3h 41m. The distance is 1,498 mi.

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