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Cheap flights from Madrid to Santa Cruz

One-way from €394, found by travellers in the last 7 days. The live price is checked when you book.

Departure
Return
Prices for nearby dates
Wed, Feb 17Any priceThu, Feb 18Any priceFri, Feb 19Any priceSat, Feb 20€394Sun, Feb 21Any priceMon, Feb 22Any priceTue, Feb 23Any priceWed, Feb 24Any price

Cheapest one-way tickets

Recent finds on different dates, for 1 adult. Booking opens on Aviasales, which shows baggage, fare rules and the live price.

Cheapest
€394
avianca airlines, flight AV 27Found 7 days ago, 1 adult
Check live price
08:10MadridSat, Feb 20
Travel time 14h 30m, 1 stopMADVVI
17:40Santa CruzSat, Feb 20
€452
Air Europa, flight UX 8755Found 3 days ago, 1 adult
Check live price
11:05MadridTue, Nov 17
Travel time 14h, 1 stopMADVVI
20:05Santa CruzTue, Nov 17
€507
Air Europa, flight UX 1159Found 4 days ago, 1 adult
Check live price
06:30MadridTue, Nov 24
Travel time 15h, 2 stopsMADVVI
16:30Santa CruzTue, Nov 24
Cheapest nonstop
€516
Air Europa, flight UX 25Found yesterday, 1 adult
Check live price
23:35MadridMon, Jan 4
Travel time 11h 20m, nonstopMADVVI
05:55Santa CruzTue, Jan 5
€572
avianca airlines, flight AV 027Found 6 days ago, 1 adult
Check live price
08:10MadridTue, Dec 29
Travel time 14h 30m, 1 stopMADVVI
17:40Santa CruzTue, Dec 29

Round trips

The cheapest return tickets found recently, price for the whole trip.

Plan the rest of the trip

  • Mobile data in BoliviaTravel eSIM from $7.50, installed before you fly.
    Compare plans
  • Getting from the airportTransfers and car hire in Santa Cruz, booked ahead at a fixed price.
    See options
  • Travel insuranceTravel insurance quotes for Bolivia from EKTA; check what each policy covers.
    Get a quote
  • Flight delayed?Arrived 3+ hours late, cancelled at short notice or bumped? Up to €600 per person under EU261.
    Check

Price calendar

The lowest one-way fare found for each day over the next 60 days. A dash means no recent fare; you can still pick that day.

October 2026

MoTuWeThFrSaSu12345678910111213141516171819202122232425–26–27–28–29–30–31–

November 2026

MoTuWeThFrSaSu1–2–3€8224€7255–6–7–8–9–10–11–12–13–14–15–16–17€45218–19€61420€64421–22–23€65024€50725–26–27–28–29–30–

December 2026

MoTuWeThFrSaSu1–2–3–4–5–6–7–8–9–10–11–12–13–14–15–16–17€81918–19–20–21–22–23€7992425262728293031
€507 or lessGreen: the cheapest fifth of fares on this route. Lowest in these 60 days: Nov 17, €452.

Lowest fares by month

In the fares found this week, February 2027 has the lowest: from €394 one-way, against €572 in December. Pick a month to see its cheapest date.

  1. Octno fares yet
  2. Nov€452
  3. Dec€572
  4. Jan€516
  5. Feb€394
  6. Marno fares yet
  7. Aprno fares yet
  8. Mayno fares yet
  9. Junno fares yet
  10. Julno fares yet
  11. Augno fares yet
  12. Sepno fares yet
€0€200€400€600OctNovDecJan€394FebMarAprMayJunJulAugSep
Show as a table
MonthCheapest one-wayDateStops
October—
November€452Tue, Nov 171 stop
December€572Tue, Dec 291 stop
January 2027€516Mon, Jan 4Nonstop
February 2027€394Sat, Feb 201 stop
March 2027—
April 2027—
May 2027—
June 2027—
July 2027—
August 2027—
September 2027—

Questions travellers ask

What is the cheapest month to fly from Madrid to Santa Cruz?

In the fares found this week, February 2027 has the lowest: from €394 one-way, against €572 in December.

Are there direct flights from Madrid to Santa Cruz?

Yes. Recent fares include nonstop flights with Air Europa.

How long is the flight from Madrid to Santa Cruz?

A nonstop flight takes about 11h 20m. The distance is 8,915 km.

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